At around 4pm yesterday afternoon police were called to an incident near a takeaway in Manchester Road.
A 52-year-old man had a wound to his back and was being treated by paramedics. He has been taken to Aintree Hospital with an injury which is believed to be serious.
The suspect is described as white, 5ft 10ins with light coloured hair. He was wearing a grey tracksuit.
Officers are in their early stages of the investigation and are making a search of the area.
Anyone with information should contact Cheshire Police on 101 quoting IML 284852. Alternatively information can be given by calling Crimestoppers on 0800 555 111